Myc's broad reach

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Myc's broad reach.

The role of the myc gene family in the biology of normal and cancer cells has been intensively studied since the early 1980s. myc genes, responding to diverse external and internal signals, express transcription factors (c-, N-, and L-Myc) that heterodimerize with Max, bind DNA, and modulate expression of a specific set of target genes. Over the last few years, expression profiling, genomic bin...

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Palm reach

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ژورنال

عنوان ژورنال: Genes & Development

سال: 2008

ISSN: 0890-9369

DOI: 10.1101/gad.1712408